.S Source code file (Many applications).
.S Temporary/Backup/Save file.
.S37 Modem installation files (Rockwell 56KFlex Modemwave/Genius series).
.S3D Simply 3D format image file (Micrografx Simply 3D).
.S3M ScreamTracker Module audio file (Many audio/tracker applications).
.SAF Safe file (Encryption and database applications).
.SAF Safe file (InterTrust).
.SAFE SafeIT encyrpted file/attachment. Original filename with extension has the SAFE extension appended to it once encryption is completed (SoftNet Security's SafeIT Encryption v6).
.SAM Ami Pro document (Many word processor and Office applications).
.SAM Headerless 16-bit monophonic audio sample file (Many audio applications).
.SAM Session file (MAGIX Music Studio).
.SAMPLE Sample file = TXT file (Ares Galaxy and others).
.SAMPLE Sample file whose content usually is that of a file with a different extension (Many applications).
.SAP Slight Atati Player/SAP audio file = a file containing music data and music player program code. See Wiki and Piotr's description of the SAP format (Piotr Fusik's Another Slight Atati Player/ASAP).
.SAS SAS source code file.
.SAV Backup files (Many applications).
.SAV Game Save file (Activision Mech Warrior 2).
.SAV Game Save or Auto-game-save file (Valve, Westwood, FreeCiv, and other games/developers).
.SAV Project or application state Save files (Many applications).
.SAZ Session Archive ZIP format (Fiddler web debugger).
.SBD Storyboard file (MGI VideoWave, a few variants).
.SBE SpyBot Excludes file = DOS text (Safer-Networking's Spybot Search & Destroy).
.SBI SpyBot Search & Destroy's Includes file = spyware detection database (Safer-Networking's OpenSBI Editor and SpyBot Search & Destroy).
.SBL StarBasic Language file (Sun's StarOffice 5.1).
.SBS SpyBot Search & Destroy Supplemental spyware detection database file (Safer-Networking's SpyBot Search & Destroy).
.SC SuperCollider file (James McCartney and others' SuperCollider).
.SC2 Schedule+ application file (Microsoft Office).
.SC9 Suitcase 9 font database file (Extensis Suitcase 9).
.SCA Scenery Assembler source file for creating Microsoft Flight Simulator 5 map sceneries (Manfred Moldenhauer's SCASM/Scenery Assembler).
.SCALA Scala programming language source code file.
.SCAMFS_CATALOG Audio file catalog (ScanFS).
.SCC StarOffice storage document (StarOffice Writer 5.1).
.SCD Animated Screen Data file (3D GIF Designer).
.SCD Schedule+ application file (Microsoft Office).
.SCD Scribus Document format same as SLA (Scribus).
.SCD SuperCollider language file (James McCartney and others' SuperCollider).
.SCE Scribus object file (Scribus).
.SCE Secure/encrypted file (SoftNet Security's SafeIT Encryption).
.SCH Schedule+ application file (Microsoft Office).
.SCH Circuit Schematic file (Michael Margraf's QUCS/Quite Universal Circuit Simulator).
.SCHLP SuperCollider Help file (James McCartney and others' SuperCollider).
.SCI SciFAX image file (Many graphics applications).
.SCL Scala tuning file.
.SCM Sound Scheme file (Mirabilis ICQ2000a).
.SCM Scheme programming language source file.
.SCN Auto-saved game (LinCity-NG) User saved games are same format without the extension.
.SCN Caligari trueSpace Scene file (Caligari trueSpace and many applications and environments).
.SCN LightWave Scene file (LightWave Studio).
.SCN Scenario file (Microsoft's Age of Empires 2).
.SCN VideoWave Scene file (MGI VideoWave 5).
.SCO Score file (Many audio/music composing/creating applications).
.SCP Script file (Many applications).
.SCPT AppleScript file (Applications supporting the AppleScript scripting language).
.SCR Frame script file (OpenFX Animator).
.SCR Monitor/Screen configuration file.
.SCR Scratchpad file (CIX's Ameol2).
.SCR Screen image file (ZX Spectrum computer).
.SCR Screensavers (Microsoft Windows).
.SCR Script file (Half-Life game engine).
.SCR Word 5.x Screen Capture image file (Microsoft Word and image editors).
.SCRATCHP Archived Scratchpad file (CIX's Ameol2).
.SCSU Unicode compressed file (Andrew West's BabelPad).
.SCT SciTex Continuous Tone image file (Many graphics applications).
.SCT Screen Template file (Microsoft Visual FoxPro 6).
.SCT Script file.
.SCX Form file (Microsoft Visual FoxPro 6).
.SD Script Definition file (Visicom Media's AceHTML Pro).
.SD Sound Designer audio file (Sound Designer and other applications).
.SD2 Sound Designer 2 audio file (QuickTime 7.7.2).
.SD4 Smart Diary Suite version 4 diary database file (Programming Sunrise's Smart Diary Suite 4).
.SD4-JOURNAL Smart Diary Suite version 4 Journal file (Programming Sunrise's Smart Diary Suite 4).
.SD4LF Smart Diary Suite version 4 Life Factors package file (Programming Sunrise's Smart Diary Suite 4).
.SD6 SafeIT address book file (SoftNet Security's SafeIT Encryption v6).
.SDA Self-Dissolving Archive (Formats unique to each machine supporting such formats).
.SDA StarDraw image file (StarOffice Draw 5.1).
.SDADDIN Sharp Develop AddIn installation package file (sharpdevelop.net's JSharp Develop 4).
.SDB SafeIT address book Database file (SoftNet Security's SafeIT Encryption).
.SDC StarCalc spreadsheet file (StarOffice Calc 5.1).
.SDD StarImpress presentation Document file (StarImpress Writer 5.1).
.SDE Equaliser settings file (Steven Mayall's MusicBee).
.SDF SQL Server Database File (Many applications).
.SDF System Data Format file = simiular to CSV and TSV, a file with fixed-length records delimited by a carriage return and line feed characters (Database applications).
.SDG Clip art thumbnail Gallery resource (IBM Lotus Symphony).
.SDL Service Description Language file (Microsoft VisualStudio).
.SDL SmartDraw image/shape Library file (SmartDraw).
.SDM StarMessage 5.0 e-mail file (Sun's StarOffice StarMessage e-mail client).
.SDP Session Description Protocol (QuickTime 7.7.2).
.SDR SmartDraw Drawing file (SmartDraw).
.SDS SpyBot Search & Destroy Script file (Safer-Networking's SpyBot Script Editor 2).
.SDS StarOffice binary Chart file (Older versions of Sun's StarOffice).
.SDSB SpyBot Search & Destroy Script Binary file = compiled script(Safer-Networking's SpyBot Script Editor 2).
.SDT SmartDraw Template drawing file (SmartDraw).
.SDV 3GPP movie (QuickTime 7.7.2).
.SDV SmartDraw Advisor image file (SmartDraw).
.SDW StarWriter document file (StarOffice Writer 5.1).
.SEA Macintosh OS Self-Extracting Archive file (SmithMicro Stuffit).
.SEC Secure/encrypted file (SoftNet Security's SafeIT Encryption).
.SEL EzyPage file (EzyWare's EzyPage).
.SES Multi-track Session file (Syntrillium Cool Edit Pro).
.SESSION Saved Session file (Neil Hodgson's SciTE).
.SESX Multi-track Session file (Adobe Audition).
.SET Character mapping base Set file (Word Perfect Office X6).
.SETTINGS Settings file (Cinta Software's CintaNotes).
.SF2 E-mu/Creative SoundFont 2 MIDI file (Many applications).
.SFARK SoundFont Archive file = compressed SoundFont file (Many audio/arrangement applications).
.SFARR SynthFont Arrangement file (Kenneth Rundt's SynthFont).
.SFD Commodore SFD 1001 disk drive disk image file (Commodore computer emulators/utilities).
.SFD Source File Data file = Font glyph data (FontForge).
.SFF Elecbyte Sprite File (Jon Rafkind's Paintown).
.SFS Orion Song Files (Sonic Syndicate Orion).
.SFS StarFrame Frameset document file (StarOffice Frame 5.1).
.SFW Sound Forge Workspace file (Sonic Foundry Sound Forge).
.SGF Sonique player Skin file (Sonique Media Systems).
.SGI SGI truecolor image file (Many image editors).
.SGL StarWriter master/Global document file (StarOffice Writer 5.1).
.SGM SGML template file / auto-file (Word Perfect Office X6).
.SGN Sign document file (Sierra On-Line's Print Artist 3).
.SH Command line Bash Shell script = batch of consecutively executed shell commands (Bash shell on Unix/Linux OSs).
.SH Mindjongg saved game (Minder Mindjongg).
.SH3 Harvard Graphics format image.
.SH3D Sweet Home 3D project file = ZIP archive.
.SHADE RayShade file (Lintermann und Deussen's/Greenworks' XFrog 3 and other applications).
.SHADOW Shadow file (Neuber Font Twister).
.SHAPE Vector-based grayscale shape image (Dia).
.SHD Bryce 2 materials file (MetaCreations Bryce 2).
.SHG Segmented Hypergraph image file (Ulead Video Paint and other graphics applications).
.SHN Shorten audio file = a popular compressed lossless audio format (Many audio editing/playing applications).
.SHP ESRI Shape file (Autodesk 3DStudio, LibreCAD, CorelCAD, and many other drawing/modelling applications).
.SHP Shalom Help Project file (Shalom Help Maker).
.SHW Presentations file (Corel Presentations).
.SHX Shape file.
.SID MrSID image file (LizardTech MrSID).
.SID SID chip music file (SIDPlayer and other 6581/SID chip emulating players).
.SIDX Stuffit Deluxe Extended format archive file (SmithMicro Stuffit Deluxe and Stuffit Expander).
.SIF Setup Information File (driver installers - SiS, Cmedia, and others).
.SIFZ Synfig animation image file (Synfig Studio).
.SIG Sign/poster project file (MindScape PrintMaster).
.SIMDT Software Ideas Modeller Documentation Template file (Dusan Rodina's Software Ideas Modeller).
.SIMP Software Ideas Modeller Project file (Dusan Rodina's Software Ideas Modeller).
.SIMSS Software Ideas Modeller StyleSets file (Dusan Rodina's Software Ideas Modeller).
.SIMT Software Ideas Modeller Template file (Dusan Rodina's Software Ideas Modeller).
.SIRENSKIN Siren Skin file (Sonic Foundry Siren/SirenXpress).
.SIT Stuffit format archive file (Smith Micro's Stuffit Deluxe,Smith Micro's Stuffit Expander, and other archiving applications).
.SITX Stuffit Extended format archive file (SmithMicro Stuffit Deluxe and Stuffit Expander).
.SK1 sK1 vector graphics file (sK1 Team's UniConvertor 1.1.5).
.SKA SSEYO Koan Album file (SSEYO Koan Album Player).
.SKB SketchBoard sketch data file (Pojchara Jatupoj's SketchBoard).
.SKD SSEYO Koan Design file (SSEYO Koan Album Player).
.SKF SketchUp thumbnail image file (Autodesk SketchUp).
.SKL System Library file (Windows operating system).
.SKM SSEYO Koan Mix file (SSEYO Koan Album Player).
.SKN Skin file (Earjam Internet Music Player 1.0).
.SKP SketchUp Component file (Autodesk SketchUp, Google Sketchup, and others).
.SKP SSEYO Koan Play file (SSEYO Koan Album Player).
.SKT SSEYO Koan Template file (SSEYO Koan Album Player).
.SL Shading Language file = RenderMan Shading Language (Timothy M Shead's K-3D 0.8).
.SLA Scribus Layout format document file = UTF-8 encoded XML document native to the open source Scribus desktop publishing application. A few variants of the format, though all should handle them correctly.
.SLD Slide file (Pierre-e Gougelet's XnView).
.SLD Styled Layer Descriptor file (GeoServer 2).
.SLK SYLK format spreadsheet or formulas file (Many Office applications).
.SLMETA Shading Language Metafile (Timothy M Shead's K-3D 0.8).
.SLN Solution file (Microsoft VisualStudio).
.SLN Solutions file (sharpdevelop.net's JSharp Develop 4).
.SLP SLP file (ArtDesk SLP Writer).
.SLP SLP render file (Parametric Technologies' Pro/Engineer).
.SMD StarMessage Document file (Sun's StarOffice StarMessage e-mail client).
.SMF MIDI file (QuickTime 7.7.2).
.SMF Simple Model Format file (Leadwerks 3D World Studio).
.SMF StarMath Mathematical Formula file (Sun's StarOffice StarMath).
.SMI SmartIcons bar configuration file (Lotus Development's Lotus Organizer).
.SMI SMIL/Synchronized Multimedia Integration Language file (QuickTime 7.7.2).
.SMIL SMIL/Synchronized Multimedia Integration Language file (QuickTime 7.7.2).
.SMIS Submitter Mission file (FirstPlace Software's WebPosition Gold).
.SMK Smacker archive file.
.SML Shape Markup Language image format. Vector based grayscale image (Kivio and other applications).
.SML SMIL/Synchronized Multimedia Integration Language file = XML markup (QuickTime 7.7.2).
.SMP NN19 Sampler device patch file (Propellerhead's Reason).
.SMP Sound sample/audio file (SampleVision).
.SMTP SMTP/Simple Mail Transfer Protocol mailserve locations file (DesertFish Roamer).
.SNAPSHOT Snapshot of storage usage in mixed file of ANSI and UTF8 (Saleen Software File Pro - A Spacemonger clone in Delphi).
.SND AU audio file (QuickTime 7.7.2).
.SNIPPET Code Snippet file (Microsoft VisualStudio).
.SNP Snapshot file (Microsoft Snapshot Viewer).
.SO Source or splash screen file (Cincom VisualWorks SmallTalk).
.SO Subversion Object file (Tigris Subversion).
.SOB Caligari Object file (Caligari for the Amiga OS).
.SOB StarOffice BASIC application file (Sun's StarOffice and OpenOffice suites).
.SOC StarOffice Configuration file (Sun's StarOffice and OpenOffice suites).
.SOD StarOffice Definition file (Sun's StarOffice and OpenOffice suites).
.SOE StarOffice Extension file (Sun's StarOffice and OpenOffice suites).
.SOS SingOutStrong playlist file (Jan Fabirkiewicz' SingOutStrong Karaoke Player).
.SOU Source code file (Cincom VisualWorks SmallTalk).
.SP6 SafeIT Secure Profile file (SoftNet Security's SafeIT Encryption v6).
.SPA Splash movie (Macromedia FutureSplash and Flash supporting applications).
.SPD form-Z Suspended render file (form-Z RadioZity).
.SPF Crontab file (ActiveState's Komodo Edit).
.SPF Shorthand glossary file (Bartels Media PhraseExpress).
.SPL Splash file (Macromedia FutureSplash and some Flash supporting applications).
.SPOP Inter Trust file.
.SPP Serif PhotoPlus animation file (Serif PhotoPlus).
.SPP Serif PhotoPlus Picture file (Serif PhotoPlus).
.SPR Screen Program file (Microsoft Visual FoxPro 6).
.SPX Ogg Speex format audio file (Many audio applications).
.SQL SQL database file (Many applications).
.SQL Structured Query Language source code or procedure file (Many variants, operating systems, and applications).
.SQLITE SQLite database file (Many applications).
.SQT Squirt save file (Squirt/ISQ).
.SR2 Sony RAW Format image file (Sony cameras, many image applications, many variants).
.SRB Scrapbook file (Word Perfect Office X6).
.SRF Sony RAW Format image file (Sony cameras, many image applications, many variants).
.SRI Scrapbook Index file (Word Perfect Office X6).
.SRL Secure Request Letter = plaintext e-mails/messages to recipients (SoftNet Security's SafeIT Encryption).
.SRP Script files (various programs).
.SRT SubRip format sub-titles file (Aegisub).
.SRT SubRip format sub-titles file (Many media player applications).
.SS Slide Show Project file (Anix Software's MySlideShow 2).
.SS Scheme programming language source file.
.SS Simple Sudoku format saved game file (SimpleSudoku, Bernhard Hobiger's HoDoKu and other Sudoku games).
.SSA Advanced Substation Alpha format sub-titles file (Aegisub).
.SSD SnagIt Studio project file (TechSmith SnagIt).
.SSF Slideshow File (Bruno Cancelleri Pictoscope).
.SSG Scrabble3D Saved Game file (Heiko Tietze's Scrabble3D).
.SSK SmartSketch drawing format image file (Macromedia SmartSketch/Flash MX and other Flash applications).
.SSM Standard Streaming Metafile (Real Networks' RealPlayer 7).
.SSP Screen Saver Project file (MGShareware Screen Saver Builder).
.SSP SSuite format Presentation file (SSuite Office Presentations).
.SSS Soysal Setup batch command file (Soysal Setup Interpreter).
.SST Microsoft Serialized certificate Store file.
.SSX Slide Show Project file (Anix Software's MySlideShow 3).
.ST SmallTalk file-outs file (Cincom VisualWorks SmallTalk).
.STAT Statistics file (Ari Pikivirta's Home FTP Server).
.STC StarOffice Calc Template file = XML based file (Sun's StarOffice and other OpenOffice suites).
.STD StarOffice Draw Template file = XML based file (Sun's StarOffice and other OpenOffice suites).
.STD Sure Thing CD label, card, or jewel case Design file (Sure Thing CD Labeler).
.STDL-BACKUP Swift To Do List database auto-backup file (Dextronet Task List Guru).
.STDL Swift To Do List database file (Dextronet Task List Guru).
.STEP STEP format 3D geometry file (Many CAD/CAM and 3D design applications).
.STH SampleTank instrument Header file (VST sound module requires .STI and .STW).
.STI SampleTank Instrument program file (VST sound module requires .STH and .STW).
.STI StarOffice Impress Template file = XML based file (Sun's StarOffice and other OpenOffice suites).
.STI Sticker project file (MindScape PrintMaster).
.STK Stock file (DTLink Software's Personal Stock Monitor 5).
.STL EBU Sub-Titling data exchange format file (Aegisub).
.STL Stereo Lithography file (Many molding, modelling and prototyping applications and devices).
.STP e-Store Project file (Trellian eCommPRO).
.STT Say The Time reminders file (Impaque Technology's Say The Time).
.STT Sure Thing CD Template file (Sure Thing CD Labeler).
.STUFFITTASK Stuffit Task file (SmithMicro Stuffit Deluxe).
.STW SampleTank instrument Waveform file (VST sound module requires .STH and .STI).
.STW StarOffice Writer Template = XML based file (Sun's StarOffice and other OpenOffice suites).
.STY Story file = text (Stepware's AceReader Pro).
.STY Style file (Pixel Studio Pro).
.SUB MicroDVD format sub-titles file (Many media player applications and sub-title editors).
.SUB Sub channel data file for audio discs (Many disk image writer/creator applications).
.SUB Subvein map file (Ben Johnson's Subvein).
.SUP PGS/SUP subtitles file (Video audio applications).
.SVA Sensiva plug-in Application file (Sensiva for Windows 2).
.SVE Saved game file (Simutrans).
.SVG Scalable Vector Graphics (Many).
.SVG Scalable Vector Graphics 2D image format. An open standard that is well supported by many applications.
.SVGZ Compressed Scalable Vector Graphics 2D image format.
.SVI Samsung format Video file (Samsung products and third party supporting applications).
.SVM Sensiva Action file (Sensiva for Windows 2).
.SVM StarView Metafile = SVG file (Sun's StarOffice 5.1).
.SVS Sensiva Symbol file (Sensiva for Windows 2).
.SVT Sensiva sound Theme file (Sensiva for Windows 2).
.SVX Amiga 8SVX format IFF audio file (Audio editor/player applications).
.SWA MPEG Layer-3 audio file (QuickTime 7.7.2).
.SWF Shockwave Flash movie file (Macromedia Flash and third party Shockwave/Flash supporting applications).
.SWP Screen Writer Project file (Virtual Amnesia's Screen Writer Pro).
.SWP Swap file (Dyvision Works' Advanced Landscape Editor).
.SWT Template file (Macromedia Generator).
.SXC StarOffice XML Calc file (Sun's StarOffice and other OpenOffice suites).
.SXD OpenOffice Drawing vector based image format. Like ODG image files, these enjoy support in the open source Office suites, and third-party Office programs.
.SXG StarOffice XML master document (Sun's StarOffice and OpenOffice suites).
.SXI StarOffice XML Impress document (Sun's StarOffice and OpenOffice suites).
.SXM StarOffice XML Math formula file (Sun's StarOffice and other OpenOffice suites).
.SXT NNXT Sampler device patch file (Propellerhead's Reason).
.SXW StarOffice XML Writer document (Sun's StarOffice and other OpenOffice suites).
.SY3 Harvard Graphics format image file.
.SYLK Symbolic Link interchange format file = text (Many applications - see Wikipedia SYLK page).
.SYN Synthesizer instrument file (FruityLoops, SimSynth, and other samplers, mixers, and trackers).
.SYX Raw SysEx file (MIDI, sequencer, sampler and other audio applications).
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